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A novel function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease

Neurodegenerative diseases such as Alzheimer's (AD) are characterized by an abnormal aggregation of misfolded beta-sheet rich proteins such as β-amyloid (Aβ). Various ubiquitously-expressed molecular chaperones control the correct folding of cellular proteins and prevent the accumulation of har...

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Detalhes bibliográficos
Main Authors: Hoshino, Akina, Helwig, Michael, Rezaei, Sina, Berridge, Casey, Eriksen, Jason L., Lindberg, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946950/
https://ncbi.nlm.nih.gov/pubmed/24102330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12454
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