PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia

Myelodysplastic syndrome (MDS) is characterized by ineffective hematopoiesis with resultant cytopenias. Increased apoptosis and aberrantly functioning progenitors are thought to contribute to this phenotype. As is the case for other malignancies, overcoming apoptosis is believed to be important in p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Guirguis, A A, Slape, C I, Failla, L M, Saw, J, Tremblay, C S, Powell, D R, Rossello, F, Wei, A, Strasser, A, Curtis, D J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987724/
https://ncbi.nlm.nih.gov/pubmed/26742432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.159
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