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Myeloid progenitor cluster formation drives emergency and leukemic myelopoiesis

While many aspects of blood production are now well understood, the spatial organization of myeloid differentiation in the bone marrow (BM) remains unknown. Here, we use imaging to track granulocyte/macrophage progenitor (GMP) behavior during emergency and leukemic myelopoiesis. At steady state, we...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Hérault, Aurélie, Binnewies, Mikhail, Leong, Stephanie, Calero-Nieto, Fernando J., Zhang, Si Yi, Kang, Yoon-A, Wang, Xiaonan, Pietras, Eric M., Chu, S. Haihua, Barry-Holson, Keegan, Armstrong, Scott, Göttgens, Berthold, Passegué, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383507/
https://ncbi.nlm.nih.gov/pubmed/28355185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21693
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