Regulation of DJ-1 by glutaredoxin 1 in vivo – implications for Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the substantia nigra. Mutations in PARK7 (DJ-1) result in early onset autosomal recessive PD, and oxidative modification of DJ-1 has been reported to regu...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Johnson, William M., Golczak, Marcin, Choe, Kyonghwan, Curran, Pierce L., Miller, Olga Gorelenkova, Yao, Chen, Wang, Wenzhang, Lin, Jiusheng, Milkovic, Nicole M., Ray, Ajit, Ravindranath, Vijayalakshmi, Zhu, Xiongwei, Wilson, Mark A., Wilson-Delfosse, Amy L., Chen, Shu G., Mieyal, John J.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987251/
https://ncbi.nlm.nih.gov/pubmed/26894491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01132
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