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Regulation of DJ-1 by glutaredoxin 1 in vivo – implications for Parkinson’s disease
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the substantia nigra. Mutations in PARK7 (DJ-1) result in early onset autosomal recessive PD, and oxidative modification of DJ-1 has been reported to regu...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987251/ https://ncbi.nlm.nih.gov/pubmed/26894491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01132 |
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