Regulation of DJ-1 by glutaredoxin 1 in vivo – implications for Parkinson’s disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide, caused by the degeneration of the dopaminergic neurons in the substantia nigra. Mutations in PARK7 (DJ-1) result in early onset autosomal recessive PD, and oxidative modification of DJ-1 has been reported to regu...

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發表在:Biochemistry
Main Authors: Johnson, William M., Golczak, Marcin, Choe, Kyonghwan, Curran, Pierce L., Miller, Olga Gorelenkova, Yao, Chen, Wang, Wenzhang, Lin, Jiusheng, Milkovic, Nicole M., Ray, Ajit, Ravindranath, Vijayalakshmi, Zhu, Xiongwei, Wilson, Mark A., Wilson-Delfosse, Amy L., Chen, Shu G., Mieyal, John J.
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987251/
https://ncbi.nlm.nih.gov/pubmed/26894491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01132
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