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Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of Cyclin E that promotes DNA replication. ORC1, the Origin Recognition Complex (ORC) large subunit, is inherited into newly born cells after it binds to condensing chromosomes...

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Vydáno v:eLife
Hlavní autoři: Hossain, Manzar, Stillman, Bruce
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987141/
https://ncbi.nlm.nih.gov/pubmed/27458800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12785
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