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Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription

Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of Cyclin E that promotes DNA replication. ORC1, the Origin Recognition Complex (ORC) large subunit, is inherited into newly born cells after it binds to condensing chromosomes...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hossain, Manzar, Stillman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987141/
https://ncbi.nlm.nih.gov/pubmed/27458800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12785
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