Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle
Cdc6p and the origin recognition complex (ORC) are essential for assembly of a pre-replicative complex (preRC) at origins of replication, before the initiation of DNA synthesis. In the absence of Cdc6p, cells fail to initiate DNA replication and undergo a “reductional” mitosis, in which the unreplic...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11572976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.201387198 |
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