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Cdc6 ATPase ACTIVITY REGULATES ORC-Cdc6 STABILITY AND THE SELECTION OF SPECIFIC DNA SEQUENCES AS ORIGINS OF DNA REPLICATION

DNA replication, as with all macromolecular synthesis steps, is controlled in part at the level of initiation. Although the Origin Recognition Complex (ORC) binds to origins of DNA replication, it does not solely determine their location. To initiate DNA replication ORC requires Cdc6 to target initi...

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Hlavní autoři: Speck, Christian, Stillman, Bruce
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033201/
https://ncbi.nlm.nih.gov/pubmed/17314092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700399200
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