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ATPase-dependent, cooperative binding of ORC and Cdc6p to origin DNA
Binding of Cdc6p to the Origin-Recognition-Complex (ORC) is a key step in the assembly of a pre-replication complex (pre-RC) at origins of DNA replication. ORC recognizes specific origin DNA sequences in an ATP-dependent manner. Here we demonstrate cooperative binding of Saccharomyces cerevisiae Cdc...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952294/ https://ncbi.nlm.nih.gov/pubmed/16228006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1002 |
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