Pigment epithelium-derived factor (PEDF) normalizes matrix defects in iPSCs derived from Osteogenesis imperfecta Type VI

Osteogenesis imperfecta (OI) Type VI is characterized by a defect in bone mineralization, which results in multiple fractures early in life. Null mutations in the PEDF gene, Serpinf1, are the cause of OI VI. Whether PEDF restoration in a murine model of OI Type VI could improve bone mass and functio...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Rare Dis
Autors principals: Belinsky, Glenn S., Ward, Leanne, Chung, Chuhan
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Addendum
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986704/
https://ncbi.nlm.nih.gov/pubmed/27579219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21675511.2016.1212150
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars