Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms

An increase in autophagy characterizes pancreatic carcinogenesis, but the signals that regulate this process are incompletely understood. Because canonical Wnt/β-catenin signaling is necessary for the transition from early to advanced pancreatic intraepithelial neoplasia (PanIN) lesions, we assessed...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Gong, Jingjing, Belinsky, Glenn, Sagheer, Usman, Zhang, Xuchen, Grippo, Paul J., Chung, Chuhan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063990/
https://ncbi.nlm.nih.gov/pubmed/27557659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729962
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