Predominant cerebral cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy

Chimeric antigen receptor-modified (CAR) T cells targeting CD19 (CART19) have shown therapeutical activities in CD19+ malignancies. However, the etiological nature of neurologic complications remains a conundrum. In our study, the evidence of blood-brain barrier (BBB)-penetrating CAR T cells as a cu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Hu, Yongxian, Sun, Jie, Wu, Zhao, Yu, Jian, Cui, Qu, Pu, Chengfei, Liang, Bin, Luo, Yi, Shi, Jimin, Jin, Aiyun, Xiao, Lei, Huang, He
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986179/
https://ncbi.nlm.nih.gov/pubmed/27526682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0299-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados