Advances of CD19-directed chimeric antigen receptor-modified T cells in refractory/relapsed acute lymphoblastic leukemia

Refractory/relapsed B-cell acute lymphoblastic leukemia remains to be a significant cause of cancer-associated morbidity and mortality for children and adults. Developing novel and effective molecular-targeted approaches is thus a major priority. Chimeric antigen receptor-modified T cell (CAR-T) the...

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Udgivet i:Exp Hematol Oncol
Main Authors: Wei, Guoqing, Ding, Lijuan, Wang, Jiasheng, Hu, Yongxian, Huang, He
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391552/
https://ncbi.nlm.nih.gov/pubmed/28413717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-017-0070-9
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