Could cytokine release syndrome induce acute myelofibrosis in CD19 chimeric antigen receptor T cells therapy?

CAR-T cells therapy can give rise to most common and concerning two side effects – cytokine release syndrome (CRS) and neurotoxicity. But in our CD19 CAR-T cells therapy clinical trial, we observed 1 out of 17 patients with B-cell acute lymphoblastic leukemia (B-ALL) developed acute myelofibrosis(AM...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Lai, Xun, Sun, Yun Yan, Chang, Lung Ji, Ma, Yu Ru, Gu, Xue Zhong, Yao, Xiang Mei, Nie, Bo, Wen, Yan, Zhang, Xue Mei, Jiang, Ya Xian, Yang, Hui, Yu, Li Qun, Fang, Ming Jing, Wang, Ling, Yuan Bo, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291836/
https://ncbi.nlm.nih.gov/pubmed/32772769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2020.1791597
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