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HSV-2 ΔgD elicits FcγR-effector antibodies that protect against clinical isolates
A single-cycle herpes simplex virus (HSV) deleted in glycoprotein D (ΔgD-2) elicited high titer HSV-specific antibodies (Abs) that (i) were rapidly transported into the vaginal mucosa; (ii) elicited antibody-dependent cell-mediated cytotoxicity but little neutralization; (iii) provided complete prot...
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| Pubblicato in: | JCI Insight |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4985247/ https://ncbi.nlm.nih.gov/pubmed/27536733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88529 |
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