Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa

Receptors for the fragment crystallizable region of immunoglobulin-G (FcγRS) play an important role in linking the humoral and cellular arms of the immune response. In this study, we present a comprehensive functional comparison of 2 human Fc-receptors, FcγRI and FcγRIIa. Activation of FcγRI results...

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Publicat a:Blood
Autors principals: Dai, Xilei, Jayapal, Manikandan, Tay, Hwee Kee, Reghunathan, Renji, Lin, Gen, Too, Chien Tei, Lim, Yan Ting, Chan, Soh Ha, Kemeny, D. Michael, Floto, R. Andres, Smith, Kenneth G. C., Melendez, Alirio J., MacAry, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937993/
https://ncbi.nlm.nih.gov/pubmed/19420354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184457
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