Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa

Receptors for the fragment crystallizable region of immunoglobulin-G (FcγRS) play an important role in linking the humoral and cellular arms of the immune response. In this study, we present a comprehensive functional comparison of 2 human Fc-receptors, FcγRI and FcγRIIa. Activation of FcγRI results...

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Bibliographic Details
Published in:	Blood
Main Authors:	Dai, Xilei, Jayapal, Manikandan, Tay, Hwee Kee, Reghunathan, Renji, Lin, Gen, Too, Chien Tei, Lim, Yan Ting, Chan, Soh Ha, Kemeny, D. Michael, Floto, R. Andres, Smith, Kenneth G. C., Melendez, Alirio J., MacAry, Paul A.
Format:	Artigo
Language:	Inglês
Published:	2009
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4937993/ https://ncbi.nlm.nih.gov/pubmed/19420354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184457
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Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa

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