Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcγRI versus FcγRIIa

Receptors for the fragment crystallizable region of immunoglobulin-G (FcγRS) play an important role in linking the humoral and cellular arms of the immune response. In this study, we present a comprehensive functional comparison of 2 human Fc-receptors, FcγRI and FcγRIIa. Activation of FcγRI results...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Dai, Xilei, Jayapal, Manikandan, Tay, Hwee Kee, Reghunathan, Renji, Lin, Gen, Too, Chien Tei, Lim, Yan Ting, Chan, Soh Ha, Kemeny, D. Michael, Floto, R. Andres, Smith, Kenneth G. C., Melendez, Alirio J., MacAry, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937993/
https://ncbi.nlm.nih.gov/pubmed/19420354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-10-184457
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