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Mutants at the 2-Fold Interface of Adeno-associated Virus Type 2 (AAV2) Structural Proteins Suggest a Role in Viral Transcription for AAV Capsids

We previously reported that an amino acid substitution, Y704A, near the 2-fold interface of adeno-associated virus (AAV) was defective for transcription of the packaged genome (M. Salganik, F. Aydemir, H. J. Nam, R. McKenna, M. Agbandje-McKenna, and N. Muzyczka, J Virol 88:1071–1079, 2013, doi: http...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Aydemir, Fikret, Salganik, Maxim, Resztak, Justyna, Singh, Jasbir, Bennett, Antonette, Agbandje-McKenna, Mavis, Muzyczka, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984656/
https://ncbi.nlm.nih.gov/pubmed/27252527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00493-16
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