Interaction between Nonstructural Proteins NS4B and NS5A Is Essential for Proper NS5A Localization and Hepatitis C Virus RNA Replication

The hepatitis C virus NS5A protein is tethered to cellular membranes via an amphipathic amino-terminal helix that is inserted in-plane into the outer endoplasmic reticulum (ER)-derived membrane leaflet. The charged face of the helix faces the cytoplasm and may contribute to interactions involved in...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Biswas, Avik, Treadaway, Jason, Tellinghuisen, Timothy L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984624/
https://ncbi.nlm.nih.gov/pubmed/27252526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00037-16
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items