A Hepatitis C Virus NS5A Phosphorylation Site That Regulates RNA Replication

The hepatitis C virus NS5A protein is essential for RNA replication and virion assembly. NS5A is phosphorylated on multiple residues during infections, but these sites remain uncharacterized. Here we identify serine 222 of genotype 2a NS5A as a phosphorylation site that functions as a negative regul...

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Main Authors: LeMay, K. L., Treadaway, J., Angulo, I., Tellinghuisen, T. L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554050/
https://ncbi.nlm.nih.gov/pubmed/23115292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02154-12
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