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Charged Residues in Hepatitis C Virus NS4B Are Critical for Multiple NS4B Functions in RNA Replication
The nonstructural 4B (NS4B) protein of hepatitis C virus (HCV) plays a central role in the formation of the HCV replication complex. To gain insight into the role of charged residues for NS4B function in HCV RNA replication, alanine substitutions were engineered in place of 28 charged residues resid...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147982/ https://ncbi.nlm.nih.gov/pubmed/21680530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00858-11 |
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