A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication

Dengue virus (DENV) infection causes the most prevalent arthropod-borne viral disease worldwide. Approved vaccines are not available, and targets suitable for the development of antiviral drugs are lacking. One possible drug target is nonstructural protein 4B (NS4B), because it is absolutely require...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Chatel-Chaix, Laurent, Fischl, Wolfgang, Scaturro, Pietro, Cortese, Mirko, Kallis, Stephanie, Bartenschlager, Marie, Fischer, Bernd, Bartenschlager, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473547/
https://ncbi.nlm.nih.gov/pubmed/25926641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00867-15
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky