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All Three Domains of the Hepatitis C Virus Nonstructural NS5A Protein Contribute to RNA Binding

The hepatitis C virus (HCV) nonstructural protein NS5A is critical for viral genome replication and is thought to interact directly with both the RNA-dependent RNA polymerase, NS5B, and viral RNA. NS5A consists of three domains which have, as yet, undefined roles in viral replication and assembly. I...

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Bibliographische Detailangaben
Hauptverfasser: Foster, Toshana L., Belyaeva, Tamara, Stonehouse, Nicola J., Pearson, Arwen R., Harris, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937630/
https://ncbi.nlm.nih.gov/pubmed/20592076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00616-10
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