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The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly

Hepatitis C virus NS3-4A is a membrane-bound enzyme complex that exhibits serine protease, RNA helicase, and RNA-stimulated ATPase activities. This enzyme complex is essential for viral genome replication and has been recently implicated in virus particle assembly. To help clarify the role of NS4A i...

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Bibliografiske detaljer
Main Authors: Phan, Tung, Kohlway, Andrew, Dimberu, Peniel, Pyle, Anna Marie, Lindenbach, Brett D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020511/
https://ncbi.nlm.nih.gov/pubmed/21047963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01889-10
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