טוען...

Pathological conformations involving the amino terminus of tau occur early in Alzheimer’s disease and are differentially detected by monoclonal antibodies

Conformational changes involving the amino terminus of the tau protein are among the earliest alterations associated with tau pathology in Alzheimer’s disease and other tauopathies. This region of tau contains a phosphatase-activating domain (PAD) that is aberrantly exposed in pathological forms of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neurobiol Dis
Main Authors: Combs, Benjamin, Hamel, Chelsey, Kanaan, Nicholas M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983528/
https://ncbi.nlm.nih.gov/pubmed/27260838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.05.016
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