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Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Formation of membrane-less organelles via liquid-liquid phase separation is one way cells meet the biological requirement for spatiotemporal regulation of cellular components and reactions. Recently, tau, a protein known for its involvement in Alzheimer’s disease and other tauopathies, was found to...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kanaan, Nicholas M., Hamel, Chelsey, Grabinski, Tessa, Combs, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272632/
https://ncbi.nlm.nih.gov/pubmed/32499559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16580-3
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