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Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies

Pathological changes to the tau protein, including conformational changes and aggregation, are major hallmarks of a group of neurodegenerative disorders known as tauopathies. Among the conformational changes are alterations involving the extreme amino terminus of the protein, known as the phosphatas...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Combs, Benjamin, Kanaan, Nicholas M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818634/
https://ncbi.nlm.nih.gov/pubmed/28413156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.01.019
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