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Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
Alzheimer’s disease (AD) and other tauopathies are characterized by fibrillar inclusions composed of the microtubule-associated protein, tau. Recently, we demonstrated that the N-terminus of tau (aa 2–18) in filamentous aggregates or N-terminal tau isoforms activates a signaling cascade involving pr...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272324/ https://ncbi.nlm.nih.gov/pubmed/21794954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.06.006 |
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