Nalaganje...

The Amino Terminus of Tau Inhibits Kinesin-Dependent Axonal Transport: Implications for Filament Toxicity

The neuropathology of Alzheimer's disease (AD) and other tauopathies is characterized by filamentous deposits of the microtubule-associated protein tau, but the relationship between tau polymerization and neurotoxicity is unknown. Here, we examined effects of filamentous tau on fast axonal tran...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: LaPointe, Nichole E., Morfini, Gerardo, Pigino, Gustavo, Gaisina, Irina N., Kozikowski, Alan P., Binder, Lester I., Brady, Scott T.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739042/
https://ncbi.nlm.nih.gov/pubmed/18798283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21850
Oznake: Označite
Brez oznak, prvi označite!