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Will targeting PI3K/Akt/mTOR signaling work in hematopoietic malignancies?

The constitutive activation of phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway has been demonstrated to be critical in clinical cancer patients as well as in laboratory cancer models including hematological malignancies. Great efforts ha...

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Detalhes bibliográficos
Publicado no:Stem Cell Investig
Main Authors: Gao, Yanan, Yuan, Chase Y., Yuan, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981705/
https://ncbi.nlm.nih.gov/pubmed/27583254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.07.02
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