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Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs

It is well established that the PI3K pathway plays a central role in various cellular processes that can contribute to the malignant phenotype. Accordingly, pharmacological inhibition of key nodes in this signaling cascade has been a focus in developmental therapeutics. To date, agents targeting ups...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Markman, Ben, Dienstmann, Rodrigo, Tabernero, Josep
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248125/
https://ncbi.nlm.nih.gov/pubmed/21317449
Tagiau: Ychwanegu Tag
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