Elevated interleukin‐27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT‐1 and STAT‐3‐dependent manner

Microbial infections are a major cause of infant mortality as a result of limitations in immune defences. Interleukin‐27 (IL‐27) is a heterodimeric cytokine produced primarily by leucocytes and is immunosuppressive toward lymphocytes and leucocytes. Our laboratory demonstrated that human neonatal ma...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Jung, Joo‐Yong, Gleave Parson, Madeline, Kraft, Jennifer D., Lyda, Logan, Kobe, Brianna, Davis, Celestia, Robinson, Jembber, Peña, Maria Marjorette O., Robinson, Cory M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981608/
https://ncbi.nlm.nih.gov/pubmed/27238498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12625
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