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Elevated interleukin‐27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT‐1 and STAT‐3‐dependent manner
Microbial infections are a major cause of infant mortality as a result of limitations in immune defences. Interleukin‐27 (IL‐27) is a heterodimeric cytokine produced primarily by leucocytes and is immunosuppressive toward lymphocytes and leucocytes. Our laboratory demonstrated that human neonatal ma...
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| Publicado no: | Immunology |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981608/ https://ncbi.nlm.nih.gov/pubmed/27238498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12625 |
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