Murine myeloid-derived suppressor cells are a source of elevated levels of interleukin-27 in early life and compromise control of bacterial infection

Microbial infections early in life remain a major cause of infant mortality worldwide. This is consistent with immune deficiencies in this population. Interleukin (IL)-27 is suppressive toward a variety of immune cell types, and we have shown that production of IL-27 is elevated in humans and mice e...

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Publicado no:Immunol Cell Biol
Main Authors: Parson, Madeline Gleave, Grimmett, Juanita, Vance, Jordan K., Witt, Michelle R., Seman, Brittany G., Rawson, Travis W., Lyda, Logan, Labuda, Christopher, Jung, Joo-Yong, Bradford, Shelby D., Robinson, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536317/
https://ncbi.nlm.nih.gov/pubmed/30575117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12224
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