Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles

The transitioning of the ectodomain of gp41 from a pre-hairpin to a six-helix bundle conformation is a crucial aspect of virus-cell fusion. To gain insight into the intermediary steps of the fusion process we have studied the pH and dodecyl phosphocholine (DPC) micelle dependent trimer association o...

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Vydáno v:PLoS One
Hlavní autoři: Louis, John M., Baber, James L., Ghirlando, Rodolfo, Aniana, Annie, Bax, Ad, Roche, Julien
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981318/
https://ncbi.nlm.nih.gov/pubmed/27513582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160597
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