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Concentration-dependent structural transition of the HIV-1 gp41 MPER peptide into α-helical trimers
The membrane proximal external region (MPER) of HIV-1 gp41 contains epitopes for at least four broadly neutralizing antibodies. Depending on solution conditions and construct design, different structures have been reported for this segment. We show that in aqueous solution the MPER fragment (gp160(6...
Gorde:
| Argitaratua izan da: | Angew Chem Int Ed Engl |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755662/ https://ncbi.nlm.nih.gov/pubmed/32916024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202008804 |
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