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HIV-1 viral envelope protein gp41: An NMR investigation of dodecyl phosphocholine embedded gp41 reveals a dynamic pre-fusion intermediate conformation
Human immunodeficiency viral (HIV-1) fusion is mediated by the viral envelope gp120/gp41 complex (ENVelope glycoprotein). After gp120 shedding, gp41 is exposed and elicits membrane fusion via a cascade of conformational changes. In contrast to pre-fusion and post-fusion conformation, little is known...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156547/ https://ncbi.nlm.nih.gov/pubmed/25132083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.06.016 |
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