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Potential approaches for heterologous prion protein treatment of prion diseases

Prion diseases, or transmissible spongiform encephalopathies (TSEs) are progressive, fatal neurodegenerative diseases with no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cellular prion protein (PrP(C)) into a protease resistant inf...

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Detalles Bibliográficos
Publicado en:Prion
Autores principales: Seelig, Davis M., Goodman, Patricia A., Skinner, Pamela J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981202/
https://ncbi.nlm.nih.gov/pubmed/26636482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123372
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