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Potential approaches for heterologous prion protein treatment of prion diseases

Prion diseases, or transmissible spongiform encephalopathies (TSEs) are progressive, fatal neurodegenerative diseases with no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cellular prion protein (PrP(C)) into a protease resistant inf...

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Bibliografische gegevens
Gepubliceerd in:Prion
Hoofdauteurs: Seelig, Davis M., Goodman, Patricia A., Skinner, Pamela J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981202/
https://ncbi.nlm.nih.gov/pubmed/26636482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123372
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