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Potential approaches for heterologous prion protein treatment of prion diseases

Prion diseases, or transmissible spongiform encephalopathies (TSEs) are progressive, fatal neurodegenerative diseases with no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cellular prion protein (PrP(C)) into a protease resistant inf...

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Bibliografiske detaljer
Udgivet i:Prion
Main Authors: Seelig, Davis M., Goodman, Patricia A., Skinner, Pamela J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981202/
https://ncbi.nlm.nih.gov/pubmed/26636482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123372
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