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Nanomedicine for prion disease treatment: New insights into the role of dendrimers

Despite their devastating impact, no effective therapeutic yet exists for prion diseases at the symptomatic stage in humans or animals. Progress is hampered by the difficulty in identifying compounds that affect PrP(Sc) and the necessity of any potential therapeutic to gain access to the CNS. Synthe...

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Detalhes bibliográficos
Main Authors: McCarthy, James M., Appelhans, Dietmar, Tatzelt, Jörg, Rogers, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783103/
https://ncbi.nlm.nih.gov/pubmed/23764833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.24431
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