Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)

Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans. The ‘protein only hypothesis’ advocates that PrP(Sc)...

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Autors principals: McCarthy, James M., Franke, Markus, Resenberger, Ulrike K., Waldron, Sibeal, Simpson, Jeremy C., Tatzelt, Jörg, Appelhans, Dietmar, Rogers, Mark S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557256/
https://ncbi.nlm.nih.gov/pubmed/23383136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055282
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