A carregar...
Design, Synthesis and Structure–Activity Relationship of Functionalized Tetrahydro-β-carboline Derivatives as Novel PDE5 Inhibitors
Starting from tadalafil as a template, a series of functionalized tetrahydro-b-carboline derivatives have been prepared and identified as novel potent and selective PDE5 inhibitors. Replacing the 3,4-methylenedioxyphenyl at position 6 of tadalafil, together with elongation of the N2-methyl substitue...
Na minha lista:
| Publicado no: | Arch Pharm (Weinheim) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980839/ https://ncbi.nlm.nih.gov/pubmed/21384413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ardp.201000236 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|