Llwytho...
Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors
Two series of fused tetrahydro-β-carboline hydantoin and tetrahydro-β-carboline thiohydantoin derivatives with a pendant 2,4-dimethoxyphenyl at position 5 were synthesized, and chiral carbons at positions 5 and 11a swing from R,R to R,S, S,R, and S,S. The prepared analogues were evaluated for their...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Int J Med Chem |
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Prif Awduron: | , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Hindawi Publishing Corporation
2011
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939265/ https://ncbi.nlm.nih.gov/pubmed/27471602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/562421 |
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