Epitope Mapping of a Monoclonal Antibody Directed against Neisserial Heparin Binding Antigen Using Next Generation Sequencing of Antigen-Specific Libraries

We explore here the potential of a newly described technology, which is named PROFILER and is based on next generation sequencing of gene-specific lambda phage-displayed libraries, to rapidly and accurately map monoclonal antibody (mAb) epitopes. For this purpose, we used a novel mAb (designated 31E...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, Venza, Mario, Venza, Isabella, Donnarumma, Danilo, Bartolini, Erika, Borgogni, Erica, Bruttini, Marco, Santini, Laura, Midiri, Angelina, Galbo, Roberta, Romeo, Letizia, Patanè, Francesco, Biondo, Carmelo, Norais, Nathalie, Masignani, Vega, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980009/
https://ncbi.nlm.nih.gov/pubmed/27508302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160702
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