Functional characterization of a monoclonal antibody epitope using a lambda phage display-deep sequencing platform

We have recently described a method, named PROFILER, for the identification of antigenic regions preferentially targeted by polyclonal antibody responses after vaccination. To test the ability of the technique to provide insights into the functional properties of monoclonal antibody (mAb) epitopes,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, Venza, Mario, Venza, Isabella, Borgogni, Erica, Castellino, Flora, Midiri, Angelina, Galbo, Roberta, Romeo, Letizia, Biondo, Carmelo, Masignani, Vega, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987625/
https://ncbi.nlm.nih.gov/pubmed/27530334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31458
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