Rapid Profiling of the Antigen Regions Recognized by Serum Antibodies Using Massively Parallel Sequencing of Antigen-Specific Libraries

There is a need for techniques capable of identifying the antigenic epitopes targeted by polyclonal antibody responses during deliberate or natural immunization. Although successful, traditional phage library screening is laborious and can map only some of the epitopes. To accelerate and improve epi...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, D'Aliberti, Deborah, Venza, Mario, Borgogni, Erica, Castellino, Flora, Biondo, Carmelo, D'Andrea, Daniel, Grassi, Luigi, Tramontano, Anna, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256389/
https://ncbi.nlm.nih.gov/pubmed/25473968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114159
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