Rapid Profiling of the Antigen Regions Recognized by Serum Antibodies Using Massively Parallel Sequencing of Antigen-Specific Libraries

There is a need for techniques capable of identifying the antigenic epitopes targeted by polyclonal antibody responses during deliberate or natural immunization. Although successful, traditional phage library screening is laborious and can map only some of the epitopes. To accelerate and improve epi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, D'Aliberti, Deborah, Venza, Mario, Borgogni, Erica, Castellino, Flora, Biondo, Carmelo, D'Andrea, Daniel, Grassi, Luigi, Tramontano, Anna, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256389/
https://ncbi.nlm.nih.gov/pubmed/25473968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114159
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