Functional characterization of a monoclonal antibody epitope using a lambda phage display-deep sequencing platform

We have recently described a method, named PROFILER, for the identification of antigenic regions preferentially targeted by polyclonal antibody responses after vaccination. To test the ability of the technique to provide insights into the functional properties of monoclonal antibody (mAb) epitopes,...

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Vydáno v:Sci Rep
Hlavní autoři: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, Venza, Mario, Venza, Isabella, Borgogni, Erica, Castellino, Flora, Midiri, Angelina, Galbo, Roberta, Romeo, Letizia, Biondo, Carmelo, Masignani, Vega, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987625/
https://ncbi.nlm.nih.gov/pubmed/27530334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31458
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