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Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs

BACKGROUND: microRNAs negatively regulate gene expression at the post-transcriptional level. Mounting evidence shows that miR expression is deregulated in human cancers including head and neck squamous cell carcinoma (HNSCC). Epigenetically silenced tumor suppressor miRs may be re-expressed upon tre...

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Bibliografiske detaljer
Udgivet i:Oral Oncol
Main Authors: Datta, Jharna, Islam, Mozaffarul, Dutta, Samidha, Roy, Sounak, Pan, Quintin, Teknos, Theodoros N.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979983/
https://ncbi.nlm.nih.gov/pubmed/27086484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2016.02.015
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